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Structure of 939398-48-8
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This bench-stable, moisture-tolerant amine features a constrained cyclopentane core with two fluorine atoms at the 3-position, delivering enhanced metabolic stability and lipophilicity. The hydrochloride salt form ensures excellent solubility in aqueous systems, enabling efficient incorporation into bioactive molecules for medicinal chemistry applications.
3,3-Difluorocyclopentan-1-amine hydrochloride serves as a valuable chiral building block in medicinal chemistry, offering enhanced metabolic stability and modulated lipophilicity due to the geminal difluoro substitution. The amine functionality enables straightforward derivatization via amidation, alkylation, or reductive amination, while the hydrochloride salt ensures excellent solubility and bench stability. This compound facilitates the construction of fluorinated heterocyclic scaffolds commonly found in bioactive molecules.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: