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Structure of 93742-85-9
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5-Fluoro-3,4-dihydronaphthalen-1(2H)-one features a fluorinated dihydronaphthalene core with a ketone at the 1-position, delivering enhanced metabolic stability and altered electronic properties. This scaffold integrates readily into bioactive molecules, enabling precise tuning of lipophilicity and binding affinity in medicinal chemistry applications.
5-Fluoro-3,4-dihydronaphthalen-1(2H)-one serves as a versatile building block in medicinal chemistry, enabling the synthesis of fluorinated aromatic scaffolds via standard functional group transformations. Its fused bicyclic structure offers enhanced metabolic stability and predictable reactivity in palladium-catalyzed couplings, while the ketone functionality facilitates regioselective derivatization. Bench-stable and compatible with common protecting group strategies, it functions as a key intermediate in the development of bioactive heterocycles and API precursors.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: