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CS-W001157 4
Total: USD 88.00

Hydroxy-PEG4-acid

  • CAS No. 937188-59-5

  • Cat. No. CS-0063728
  • Purity≥97%
  • MDL No.MFCD22574805

*For research and further manufacturing use only, not for direct human use.

Hydroxy-PEG4-acid|CS-0063728

Structure of 937188-59-5

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General Information

  • CAS No. 937188-59-5
  • Cat. No. CS-0063728
  • Purity ≥97%
  • MDL No. MFCD22574805
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₂₂O₇
  • Molecular Weight 266.29
  • Synonym(s) None
  • SMILES OC(CCOCCOCCOCCOCCO)=O

Description

Hydroxy-PEG4-acid is a water-soluble, bifunctional linker featuring a terminal carboxylic acid and a hydroxyl group separated by a four-ethylene glycol unit. This structure enables efficient conjugation to biomolecules while maintaining solubility and stability under physiological conditions.

Application

Hydroxy-PEG4-acid serves as a versatile bifunctional linker for conjugation and solubilization in synthetic chemistry. Its terminal hydroxyl group enables derivatization via esterification or ether formation, while the carboxylic acid facilitates amide coupling or salt formation. The PEG4 spacer provides enhanced solubility and reduced aggregation, making it well-suited for applications in drug delivery systems, peptide modification, and the synthesis of bioconjugates requiring controlled hydrophilicity and stability under physiological conditions.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   94.45
  • LogP   -0.4802
  • H_Acceptors   6
  • H_Donors   2
  • Rotatable_Bonds   14

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