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CS-W001157 4
Total: USD 88.00

2-Phenylacetohydrazide

  • CAS No. 937-39-3

  • Cat. No. CS-0067160
  • Purity≥96%
  • MDL No.MFCD00007612

*For research and further manufacturing use only, not for direct human use.

2-Phenylacetohydrazide|CS-0067160

Structure of 937-39-3

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General Information

  • CAS No. 937-39-3
  • Cat. No. CS-0067160
  • Purity ≥96%
  • MDL No. MFCD00007612
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₀N₂O
  • Molecular Weight 150.18
  • Synonym(s) Phenylacetic hydrazide
  • SMILES O=C(NN)CC1=CC=CC=C1

Description

2-Phenylacetohydrazide features a hydrazide functional group attached to a phenyl-substituted acetyl moiety, enabling its use in heterocycle synthesis and coordination chemistry. This bench-stable compound integrates readily into multistep transformations, offering predictable reactivity in the formation of pyrazoles, triazoles, and metal complexes under standard conditions.

Application

2-Phenylacetohydrazide serves as a versatile building block in heterocyclic synthesis, enabling efficient access to hydrazine-based scaffolds. Its phenyl-substituted acetylhydrazide functionality facilitates reliable cyclization reactions, particularly in the formation of imidazoles, triazoles, and pyrazoles under standard conditions. The compound exhibits good bench stability and is compatible with common functional groups, simplifying purification and integration into multi-step synthetic sequences.

Synthesis

  • Route1
    • null|null
      101-97-3
    • ~87%
    • In-stock
      2-Phenylacetohydrazide|CS-0067160
      937-39-3

    References

    • Kudelko, Agnieszka Tetrahedron, 2011 , vol. 67, # 44 p. 8502 - 8508
  • Route2
    • null|null
      103-82-2
    • ~77%
    • In-stock
      2-Phenylacetohydrazide|CS-0067160
      937-39-3

    References

    • Elshaarawy, Reda F.M.; Janiakb, Christoph Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences, 2011 , vol. 66, # 12 p. 1202 - 1208
  • Route3
    • null|null
      101-41-7
    • ~90%
    • In-stock
      2-Phenylacetohydrazide|CS-0067160
      937-39-3

    References

    • Murty; Ram, Kesur R.; Rao, Rayudu Venkateswara; Yadav; Rao, Janapala Venkateswara; Pamanji; Velatooru Letters in Drug Design and Discovery, 2012 , vol. 9, # 3 p. 276 - 281

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301
Precautionary Statements : P264-P270-P330-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   55.12
  • LogP   0.219
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   2

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