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Structure of 93628-97-8
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(E)-1-(2-Nitrovinyl)-4-(trifluoromethyl)benzene features a conjugated nitrovinyl group attached to a trifluoromethyl-substituted aromatic ring, delivering enhanced electron-withdrawing character. This configuration enables efficient participation in Michael additions and heterocyclic cyclizations under mild conditions, offering a robust scaffold for synthetic access to bioactive nitrogen-containing compounds.
(E)-1-(2-Nitrovinyl)-4-(trifluoromethyl)benzene serves as a versatile Michael acceptor and synthetic building block in heterocyclic chemistry. Its conjugated nitroalkene moiety enables efficient nucleophilic addition reactions, while the trifluoromethyl group imparts enhanced metabolic stability and lipophilicity—key attributes in medicinal chemistry. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for use in multi-step synthesis of bioactive scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: