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CS-W001157 4
Total: USD 88.00

2-Phenylimidazoline

  • CAS No. 936-49-2

  • Cat. No. CS-0008348
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-Phenylimidazoline|CS-0008348

Structure of 936-49-2

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General Information

  • CAS No. 936-49-2
  • Cat. No. CS-0008348
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₀N₂
  • Molecular Weight 146.19
  • Synonym(s) 2-Imidazoline, 2-phenyl- (6CI,7CI,8CI); 2-Phenyl-2-imidazoline; Phenylimidazoline
  • SMILES C1(C2=CC=CC=C2)=NCCN1

Application

2-Phenylimidazoline serves as a versatile heterocyclic building block in medicinal chemistry, enabling the construction of imidazole-based scaffolds through oxidative cyclization. Its bench-stable nature and compatibility with common functional groups facilitate straightforward incorporation into drug discovery campaigns. The compound functions as a key intermediate in the synthesis of bioactive imidazolines and related nitrogen-containing heterocycles, particularly those targeting CNS receptors and kinase modulators.

Synthesis

  • Route1
    • null|null
      100-47-0
    • null|null
      107-15-3
    • ~94%
    • In-stock
      2-Phenylimidazoline|CS-0008348
      936-49-2

    References

    • An, Shujuan; Yin, Bing; Liu, Ping; Li, Xiangnan; Li, Chen; Li, Jianli; Shi, Zhen Synthesis (Germany), 2013 , vol. 45, # 18 art. no. SS-2013-H0287-OP, p. 2525 - 2532
  • Route2

    References

    • Prokopcova, Hana; Kappe, C. Oliver Advanced Synthesis and Catalysis, 2007 , vol. 349, # 3 p. 448 - 452
  • Route3
    • null|null
      107-15-3
    • In-stock
      Benzyl alcohol|CS-4355
      100-51-6
    • ~99%
    • In-stock
      2-Phenylimidazoline|CS-0008348
      936-49-2

    References

    • Ishihara, Midori; Togo, Hideo Tetrahedron, 2007 , vol. 63, # 6 p. 1474 - 1480

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07,GHS09
Signal Word : Danger
UN#: 3077
Class : 9
Packing Group : Ⅲ
Hazard Statements : H302-H315-H318-H410
Precautionary Statements : P264-P270-P273-P280-P302+P352-P330-P362+P364-P391-P501

Quality Control

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Computational Chemistry Data

  • TPSA   24.39
  • LogP   1.0364
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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