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CS-W001157 4
Total: USD 88.00

HMMNI

  • CAS No. 936-05-0

  • Cat. No. CS-W008216
  • Purity≥98%
  • MDL No.MFCD00159675

*For research and further manufacturing use only, not for direct human use.

HMMNI|CS-W008216

Structure of 936-05-0

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General Information

  • CAS No. 936-05-0
  • Cat. No. CS-W008216
  • Purity ≥98%
  • MDL No. MFCD00159675
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₇N₃O₃
  • Molecular Weight None
  • Synonym(s) Hydroxy Dimetridazole
  • SMILES OCC1=NC=C([N+]([O-])=O)N1C

Description

0

Application

HMMNI serves as a robust building block for constructing complex heterocyclic architectures, particularly in the synthesis of pyrrolo[2,3-d]pyrimidine scaffolds. Its well-defined reactivity enables efficient coupling with nucleophiles under mild conditions, offering high functional group tolerance and ease of purification. The compound exhibits excellent bench stability and compatibility with standard synthetic workflows, making it a reliable choice for medicinal chemistry and process development applications.

Synthesis

  • Route1
    • null|null
      50-00-0
    • In-stock
      1-Methyl-5-nitroimidazole|CS-W002392
      3034-42-2
    • ~82%
    • In-stock
      HMMNI|CS-W008216
      936-05-0

    References

    • Adebayo, Adelaide T. O. M.; Bowman, W. Russell; Salt, W. G. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1987 , p. 2819 - 2828
  • Route2

    References

    • ANGIOGENE PHARMACEUTICALS LIMITED; THE GRAY LABORATORY CANCER RESEARCH TRUST Patent: WO2006/32921 A1, 2006 ; Location in patent: Page/Page column 35-36 ;
  • Route3
    • 1-Methyl-5-nitro-1H-imidazole-2-carbaldehyde|CS-0732277
      4750-57-6
    • ~%
    • In-stock
      HMMNI|CS-W008216
      936-05-0

    References

    • Journal of Medicinal Chemistry, , vol. 43, # 11 p. 2258 - 2265

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS08
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H341-H351
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   81.19
  • LogP   -0.1794
  • H_Acceptors   5
  • H_Donors   1
  • Rotatable_Bonds   2

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