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Structure of 933759-45-6
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2-(Dimethylamino)pyrimidine-4-carboxylic acid features a pyrimidine core functionalized with a dimethylamino group at C2 and a carboxylic acid at C4, enabling dual coordination sites. This structural motif supports integration into metal-chelating systems and serves as a key scaffold in medicinal chemistry for modulating electronic properties and solubility in bioactive molecules.
2-(Dimethylamino)pyrimidine-4-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of pyrimidine-based scaffolds through amide coupling and Suzuki-Miyaura cross-coupling reactions. Its carboxylic acid group facilitates direct derivatization, while the dimethylamino functionality enhances solubility and modulates electronic properties. The compound exhibits bench stability and compatibility with standard purification methods, making it well-suited for iterative synthesis campaigns in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: