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1-Amino-3-methoxypropan-2-ol

  • CAS No. 93372-65-7

  • Cat. No. CS-0106474
  • Purity≥98%
  • MDL No.MFCD00462795

*For research and further manufacturing use only, not for direct human use.

1-Amino-3-methoxypropan-2-ol|CS-0106474

Structure of 93372-65-7

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General Information

  • CAS No. 93372-65-7
  • Cat. No. CS-0106474
  • Purity ≥98%
  • MDL No. MFCD00462795
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₁₁NO₂
  • Molecular Weight 105.14
  • Synonym(s) 2-hydroxy-3-methoxypropylamine
  • SMILES OC(COC)CN

Description

1-Amino-3-methoxypropan-2-ol is a bifunctional building block featuring a primary amine and a methoxy group on a propanediol scaffold. This hydroxyl-rich, moisture-tolerant molecule integrates readily into peptide mimetics and bioconjugation workflows. The pendant amine enables straightforward derivatization, while the methoxy substituent enhances solubility and metabolic stability in aqueous systems.

Application

1-Amino-3-methoxypropan-2-ol serves as a versatile bifunctional building block in synthetic chemistry, enabling the construction of heterocyclic scaffolds and peptide-like motifs. Its amine and hydroxyl groups offer orthogonal reactivity for selective derivatization, while the methoxy group enhances solubility and metabolic stability. The compound exhibits excellent bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis workflows in medicinal chemistry and process development.

Synthesis

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    • In-stock
      1-Amino-3-methoxypropan-2-ol|CS-0106474
      93372-65-7

    References

    • Ponomarew Zhurnal Obshchei Khimii, 1953 , vol. 23, p. 656,661; engl. Ausg. S. 681, 685

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   55.48
  • LogP   -1.0476
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   3

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