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CS-W001157 4
Total: USD 88.00

(3,5-Bis(ethoxycarbonyl)phenyl)boronic acid

  • CAS No. 932378-94-4

  • Cat. No. CS-0059843
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(3,5-Bis(ethoxycarbonyl)phenyl)boronic acid|CS-0059843

Structure of 932378-94-4

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General Information

  • CAS No. 932378-94-4
  • Cat. No. CS-0059843
  • Purity ≥95%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₅BO₆
  • Molecular Weight 266.05
  • Synonym(s) (3,5-bis(ethoxycarbonyl)phenyl)boronic acid(WS202795)
  • SMILES C=1(B(O)O)C=C(C(=O)OCC)C=C(C1)C(=O)OCC

Description

This boronic acid features two ethoxycarbonyl groups at the 3- and 5-positions of the phenyl ring, enhancing solubility and stability. The para-substituted boronate moiety enables efficient Suzuki-Miyaura coupling under standard conditions, facilitating rapid assembly of complex aryl architectures in synthetic and medicinal chemistry workflows.

Application

(3,5-Bis(ethoxycarbonyl)phenyl)boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl scaffolds with high functional group tolerance. The dual ester groups enhance solubility and stability, while the boronic acid moiety facilitates reliable coupling under mild conditions. Its bench-stable nature and compatibility with diverse reaction partners make it ideal for synthetic applications in medicinal chemistry and materials science.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362

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Computational Chemistry Data

  • TPSA   93.06
  • LogP   -0.2802
  • H_Acceptors   6
  • H_Donors   2
  • Rotatable_Bonds   5

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