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Structure of 932375-18-3
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4-Fluoro-2-methyl-5-nitrobenzonitrile features a trifunctional aromatic core integrating fluorine, methyl, and nitro groups ortho to a nitrile handle. This electron-deficient scaffold enables direct coupling in cross-coupling reactions and serves as a building block for bioactive heterocycles under standard conditions.
4-Fluoro-2-methyl-5-nitrobenzonitrile serves as a versatile building block for heterocyclic synthesis, enabling efficient access to substituted pyridine and quinoline scaffolds via standard cyclization protocols. The molecule’s ortho-directing nitro and cyano groups, combined with the fluorine substituent, facilitate regioselective functionalization. Bench-stable and amenable to purification by flash chromatography, it supports scalable transformations in medicinal chemistry campaigns.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: