Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

N-Methylpyrimidin-2-amine

  • CAS No. 931-61-3

  • Cat. No. CS-0061723
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

N-Methylpyrimidin-2-amine|CS-0061723

Structure of 931-61-3

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 931-61-3
  • Cat. No. CS-0061723
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₇N₃
  • Molecular Weight 109.13
  • Synonym(s) 2-Methylaminopyrimidine
  • SMILES CNC1=NC=CC=N1

Description

N-Methylpyrimidin-2-amine features a pyrimidine core with a methylated nitrogen at the 2-position, delivering enhanced solubility and metabolic stability. This bench-stable heterocycle integrates readily into pharmaceutical scaffolds, serving as a key building block in kinase inhibitor development and medicinal chemistry campaigns.

Application

N-Methylpyrimidin-2-amine serves as a versatile building block in medicinal chemistry, enabling efficient access to pyrimidine-based scaffolds. Its methylated nitrogen enhances solubility and metabolic stability while maintaining reactivity for palladium-catalyzed cross-coupling reactions. The compound functions as a key intermediate in the synthesis of kinase inhibitors and other bioactive heterocycles, offering excellent bench stability and compatibility with standard purification methods.

Synthesis

  • Route1
    • In-stock
      2-Chloropyrimidine|CS-W008600
      1722-12-9
    • null|null
      74-89-5
    • ~91%
    • In-stock
      N-Methylpyrimidin-2-amine|CS-0061723
      931-61-3

    References

    • Kanie, Kiyoshi; Mizuno, Katsuya; Kuroboshi, Manabu; Hiyama, Tamejiro Bulletin of the Chemical Society of Japan, 1998 , vol. 71, # 8 p. 1973 - 1991
  • Route2
    • 2-Amino-1-methylpyrimidin-1-ium iodide|CS-0590746
      62062-31-1
    • ~%
    • In-stock
      N-Methylpyrimidin-2-amine|CS-0061723
      931-61-3

    References

    • Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 331 - 335

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   37.81
  • LogP   0.5183
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • N-Methylpyrimidin-2-amine sigmaN-Methylpyrimidin-2-amine manufacturerN-Methylpyrimidin-2-amine priceN-Methylpyrimidin-2-amine structureN-Methylpyrimidin-2-amine SDSbuy N-Methylpyrimidin-2-amineN-Methylpyrimidin-2-amine supplierN-Methylpyrimidin-2-amine usesN-Methylpyrimidin-2-amine molecular weightprice of N-Methylpyrimidin-2-amineN-Methylpyrimidin-2-amine chemical name formula of N-Methylpyrimidin-2-amine
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label