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Structure of 931-33-9
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4-Bromo-1H-pyrrole-2-carbaldehyde features a brominated pyrrole core with an aldehyde functional group at the 2-position, enabling direct incorporation into diverse synthetic architectures. This electron-deficient heterocycle serves as a key building block in medicinal chemistry and materials science, offering high reactivity in coupling reactions and ease of derivatization under standard conditions.
4-Bromo-1H-pyrrole-2-carbaldehyde serves as a versatile building block in heterocyclic synthesis, enabling palladium-catalyzed cross-coupling reactions and functionalization at the C2 aldehyde position. Its bromo group facilitates Suzuki, Stille, or Negishi coupling, while the aldehyde functionality allows for imine formation, reductive amination, or oxidation to carboxylic acid derivatives. The compound exhibits good bench stability and is readily purified by flash chromatography, making it well-suited for iterative medicinal chemistry campaigns and API intermediate development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: