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CS-W001157 4
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tert-Butyl 3-(7-aminopyrazolo[1,5-a]pyrimidin-5-yl)piperidine-1-carboxylate

  • CAS No. 930595-69-0

  • Cat. No. CS-0529313
  • Molecule weight317.39
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

tert-Butyl 3-(7-aminopyrazolo[1,5-a]pyrimidin-5-yl)piperidine-1-carboxylate|CS-0529313

Structure of 930595-69-0

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General Information

  • CAS No. 930595-69-0
  • Cat. No. CS-0529313
  • Purity ≥98%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₆H₂₃N₅O₂
  • Molecular Weight 317.39
  • Synonym(s) 1-Piperidinecarboxylic acid, 3-(7-aminopyrazolo[1,5-a]pyrimidin-5-yl)-, 1,1-dimethylethyl ester
  • SMILES O=C(N1CCCC(C1)C2=NC3=CC=NN3C(N)=C2)OC(C)(C)C

Synthesis

  • Route1
    • tert-Butyl 3-(7-chloropyrazolo[1,5-a]pyrimidin-5-yl)piperidine-1-carboxylate|CS-0674401
      877173-81-4
    • ~96%
    • tert-Butyl 3-(7-aminopyrazolo[1,5-a]pyrimidin-5-yl)piperidine-1-carboxylate|CS-0529313
      930595-69-0

    References

    • Labroli, Marc; Paruch, Kamil; Dwyer, Michael P.; Alvarez, Carmen; Keertikar, Kartik; Poker, Cory; Rossman, Randall; Duca, Jose S.; Fischmann, Thierry O.; Madison, Vincent; Parry, David; Davis, Nicole; Seghezzi, Wolfgang; Wiswell, Derek; Guzi, Timothy J. Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 1 p. 467 - 470
  • Route2
    • null|null
      1304779-58-5
    • ~95%
    • tert-Butyl 3-(7-aminopyrazolo[1,5-a]pyrimidin-5-yl)piperidine-1-carboxylate|CS-0529313
      930595-69-0

    References

    • Dwyer, Michael P.; Paruch, Kamil; Labroli, Marc; Alvarez, Carmen; Keertikar, Kerry M.; Poker, Cory; Rossman, Randall; Fischmann, Thierry O.; Duca, Jose S.; Madison, Vincent; Parry, David; Davis, Nicole; Seghezzi, Wolfgang; Wiswell, Derek; Guzi, Timothy J. Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 1 p. 471 - 474

Safety Information

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GHS Pictogram : N/A
GHS No : N/A
Signal Word : N/A
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

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Computational Chemistry Data

  • TPSA   85.75
  • LogP   2.426
  • H_Acceptors   6
  • H_Donors   1
  • Rotatable_Bonds   1

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