Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

4-Amino-2,6-dichloronicotinic acid

  • CAS No. 929288-22-2

  • Cat. No. CS-W022067
  • Purity≥98%
  • MDL No.MFCD19105212

*For research and further manufacturing use only, not for direct human use.

4-Amino-2,6-dichloronicotinic acid|CS-W022067

Structure of 929288-22-2

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 929288-22-2
  • Cat. No. CS-W022067
  • Purity ≥98%
  • MDL No. MFCD19105212
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₄Cl₂N₂O₂
  • Molecular Weight 207.01
  • Synonym(s) 4-amino-2,6-dichloronicotinic acid hydrochloride
  • SMILES O=C(O)C1=C(Cl)N=C(Cl)C=C1N

Description

4-Amino-2,6-dichloronicotinic acid features a conjugated pyridine core bearing two chlorine substituents and a primary amine group, enabling direct integration into diverse heterocyclic scaffolds. This electron-deficient framework supports efficient coupling reactions under mild conditions, offering enhanced solubility in polar solvents and stability during synthetic manipulations.

Application

4-Amino-2,6-dichloronicotinic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its orthogonal functional groups—amino and carboxylic acid—facilitate efficient derivatization via amide coupling, amidation, or electrophilic substitution. The dichloro substitution pattern enhances reactivity in cross-coupling processes and supports structural diversification for target-focused libraries. Bench-stable and readily purified by crystallization, it functions reliably in standard synthetic workflows.

Synthesis

  • Route1

    References

    • Jang, Mi-Yeon; Jonghe, Steven De; Gao, Ling-Jie; Herdewijn, Piet Tetrahedron Letters, 2006 , vol. 47, # 50 p. 8917 - 8920
  • Route2

    References

    • Jang, Mi-Yeon; Jonghe, Steven De; Gao, Ling-Jie; Herdewijn, Piet Tetrahedron Letters, 2006 , vol. 47, # 50 p. 8917 - 8920
  • Route3

    References

    • Jang, Mi-Yeon; Jonghe, Steven De; Gao, Ling-Jie; Herdewijn, Piet Tetrahedron Letters, 2006 , vol. 47, # 50 p. 8917 - 8920

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   76.21
  • LogP   1.6688
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 4-Amino-2,6-dichloronicotinic acid sigma4-Amino-2,6-dichloronicotinic acid manufacturer4-Amino-2,6-dichloronicotinic acid price4-Amino-2,6-dichloronicotinic acid structure4-Amino-2,6-dichloronicotinic acid SDSbuy 4-Amino-2,6-dichloronicotinic acid4-Amino-2,6-dichloronicotinic acid supplier4-Amino-2,6-dichloronicotinic acid uses4-Amino-2,6-dichloronicotinic acid molecular weightprice of 4-Amino-2,6-dichloronicotinic acid4-Amino-2,6-dichloronicotinic acid chemical name formula of 4-Amino-2,6-dichloronicotinic acid
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label