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Structure of 92822-02-1
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4-(4'-Fluorobenzyl)piperidine features a fluorinated benzyl group attached to the piperidine ring, delivering enhanced metabolic stability and improved membrane permeability. This structural motif enables efficient integration into bioactive molecules, particularly in CNS-targeted pharmaceuticals and kinase inhibitors. The para-fluoro substitution imparts favorable electronic and lipophilic properties for drug design.
4-(4'-Fluorobenzyl)piperidine serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive scaffolds through its readily functionalizable piperidine core and orthogonal fluoroaryl handle. The molecule exhibits excellent bench stability, facilitates efficient derivatization via alkylation or coupling reactions, and supports high functional group tolerance—making it well-suited for iterative synthesis campaigns targeting CNS-directed therapeutics and kinase inhibitors.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: