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CS-W001157 4
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Ethyl 3-(((trifluoromethyl)sulfonyl)oxy)furo[2,3-c]pyridine-2-carboxylate

  • CAS No. 927804-63-5

  • Cat. No. CS-0321779
  • Molecule weight339.24
  • Purity95+%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Ethyl 3-(((trifluoromethyl)sulfonyl)oxy)furo[2,3-c]pyridine-2-carboxylate|CS-0321779

Structure of 927804-63-5

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General Information

  • CAS No. 927804-63-5
  • Cat. No. CS-0321779
  • Purity 95+%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₈F₃NO₆S
  • Molecular Weight 339.24
  • Synonym(s) Furo[2,3-c]pyridine-2-carboxylic acid, 3-[[(trifluoroMethyl)sulfonyl]oxy]-, ethyl ester
  • SMILES CCOC(=O)C1=C(C2=CC=NC=C2O1)OS(=O)(=O)C(F)(F)F

Synthesis

  • Route1
    • null|null
      358-23-6
    • Ethyl 3-hydroxyfuro[2,3-c]pyridine-2-carboxylate|CS-0053861
      106531-50-4
    • ~89%
    • Ethyl 3-(((trifluoromethyl)sulfonyl)oxy)furo[2,3-c]pyridine-2-carboxylate|CS-0321779
      927804-63-5

    References

    • Buckmelter, Alex J.; Ren, Li; Laird, Ellen R.; Rast, Bryson; Miknis, Greg; Wenglowsky, Steve; Schlachter, Stephen; Welch, Mike; Tarlton, Eugene; Grina, Jonas; Lyssikatos, Joseph; Brandhuber, Barbara J.; Morales, Tony; Randolph, Nikole; Vigers, Guy; Martinson, Matthew; Callejo, Michele Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 4 p. 1248 - 1252
  • Route2

    References

    • Buckmelter, Alex J.; Ren, Li; Laird, Ellen R.; Rast, Bryson; Miknis, Greg; Wenglowsky, Steve; Schlachter, Stephen; Welch, Mike; Tarlton, Eugene; Grina, Jonas; Lyssikatos, Joseph; Brandhuber, Barbara J.; Morales, Tony; Randolph, Nikole; Vigers, Guy; Martinson, Matthew; Callejo, Michele Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 4 p. 1248 - 1252
  • Route3

    References

    • GENENTECH, INC.; FORMA TM, LLC; BAIR, Kenneth W.; BAUMEISTER, Timm R.; BUCKMELTER, Alexandre J.; CLODFELTER, Karl H.; DRAGOVICH, Peter; GOSSELIN, Francis; GUNZNER-TOSTE, Janet; HAN, Bingsong; LIN, Jian; LIU, Xiongcai; REYNOLDS, Dominic J.; SMITH, Chase C.; WANG, Zhongguo; ZAK, Mark; ZHANG, Yamin; ZHAO, Guiling; ZHENG, Xiaozhang; YUEN, Po-Wai Patent: WO2013/127266 A1, 2013 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H320-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   95.7
  • LogP   2.2329
  • H_Acceptors   7
  • H_Donors   0
  • Rotatable_Bonds   4

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