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Structure of 927390-60-1
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N,N-Dimethylazetidine-3-carboxamide hydrochloride features a constrained azetidine ring with dual N-methyl substitutions, enhancing metabolic stability and solubility. The carboxamide functionality provides a hydrogen-bonding handle for molecular recognition, while the hydrochloride salt ensures excellent crystallinity and shelf stability under ambient conditions.
N,N-Dimethylazetidine-3-carboxamide hydrochloride serves as a versatile building block in medicinal chemistry, enabling efficient access to constrained amide-containing scaffolds. Its azetidine core provides enhanced metabolic stability and improved membrane permeability compared to larger heterocycles. The dimethylamino group enhances solubility and facilitates downstream functionalization, while the carboxamide functionality supports diverse coupling reactions. Bench-stable and readily purified, it functions effectively in standard peptide and small-molecule synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: