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CS-W001157 4
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N,N-Dimethylazetidine-3-carboxamide hydrochloride

  • CAS No. 927390-60-1

  • Cat. No. CS-0048831
  • Purity≥97%
  • MDL No.None
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

N,N-Dimethylazetidine-3-carboxamide hydrochloride|CS-0048831

Structure of 927390-60-1

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Description

N,N-Dimethylazetidine-3-carboxamide hydrochloride features a constrained azetidine ring with dual N-methyl substitutions, enhancing metabolic stability and solubility. The carboxamide functionality provides a hydrogen-bonding handle for molecular recognition, while the hydrochloride salt ensures excellent crystallinity and shelf stability under ambient conditions.

Application

N,N-Dimethylazetidine-3-carboxamide hydrochloride serves as a versatile building block in medicinal chemistry, enabling efficient access to constrained amide-containing scaffolds. Its azetidine core provides enhanced metabolic stability and improved membrane permeability compared to larger heterocycles. The dimethylamino group enhances solubility and facilitates downstream functionalization, while the carboxamide functionality supports diverse coupling reactions. Bench-stable and readily purified, it functions effectively in standard peptide and small-molecule synthesis workflows.

General Information

  • CAS No. 927390-60-1
  • Cat. No. CS-0048831
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₃ClN₂O
  • Molecular Weight 164.63
  • Synonym(s) 3-Azetidinecarboxamide, N,N-dimethyl-, hydrochloride
  • SMILES Cl.CN(C)C(=O)C1CNC1

Computational Chemistry Data

  • TPSA   32.34
  • LogP   -0.2842
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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