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6-(4-Amino-2,6-dichlorophenoxy)-4-isopropylpyridazin-3(2H)-one

  • CAS No. 920509-28-0

  • Cat. No. CS-0535225
  • Molecule weight314.17
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

6-(4-Amino-2,6-dichlorophenoxy)-4-isopropylpyridazin-3(2H)-one|CS-0535225

Structure of 920509-28-0

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General Information

  • CAS No. 920509-28-0
  • Cat. No. CS-0535225
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₃Cl₂N₃O₂
  • Molecular Weight 314.17
  • Synonym(s) 6-(4-amino-2,6-dichlorophenoxy)-4-isopropylpyridazin-3(2H)-one(WXG00197)
  • SMILES CC(C)C1=CC(=NNC1=O)OC2=C(C=C(C=C2Cl)N)Cl

Description

6-(4-Amino-2,6-dichlorophenoxy)-4-isopropylpyridazin-3(2H)-one features a pyridazinone core functionalized with a dichlorophenoxy ether and isopropyl substituent. This electron-deficient heterocycle integrates readily into bioactive scaffolds, offering enhanced metabolic stability and solubility in polar solvents under standard conditions.

Application

6-(4-Amino-2,6-dichlorophenoxy)-4-isopropylpyridazin-3(2H)-one serves as a versatile heterocyclic building block in medicinal chemistry, enabling the construction of advanced API scaffolds. Its pyridazinone core exhibits robust bench stability and tolerates diverse functional groups, facilitating efficient coupling reactions. The 4-amino-2,6-dichlorophenoxy moiety supports further derivatization via nucleophilic substitution or metal-catalyzed cross-coupling, enhancing structural diversity in target molecule synthesis.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   81
  • LogP   3.5746
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   3

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