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CS-W001157 4
Total: USD 88.00

3-Methylpyridin-2-ol

  • CAS No. 91914-04-4

  • Cat. No. CS-0047721
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

3-Methylpyridin-2-ol|CS-0047721

Structure of 91914-04-4

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General Information

  • CAS No. 91914-04-4
  • Cat. No. CS-0047721
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₇NO
  • Molecular Weight 109.13
  • Synonym(s) 3-Methyl-2(1H)-pyridinone
  • SMILES OC1=NC=CC=C1C

Description

3-Methylpyridin-2-ol delivers a strategically positioned hydroxyl group on a nitrogen-rich heterocycle, enabling direct incorporation into ligand architectures and catalytic scaffolds. The methyl substituent enhances electron density at the pyridinic ring while maintaining solubility in common organic solvents. This bench-stable derivative serves as a key intermediate for functionalized pyridine libraries in medicinal chemistry and materials synthesis.

Application

3-Methylpyridin-2-ol serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through established functional group transformations. Its pyridinol scaffold offers enhanced solubility and hydrogen-bonding capacity, while the methyl group provides a site for selective oxidation or further functionalization. The compound exhibits good bench stability and compatibility with standard coupling reactions, facilitating its use in iterative synthesis workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   33.12
  • LogP   1.09562
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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