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Structure of 918538-05-3
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2,4-Dichloropyrrolo[2,1-f][1,2,4]triazine is a chlorinated heterocyclic scaffold featuring a fused triazine core with strategic substitution at the 2- and 4-positions. This electron-deficient architecture enables efficient coupling in cross-coupling transformations and serves as a key building block in medicinal chemistry for targeted kinase inhibition. The molecule exhibits enhanced stability under standard conditions and facilitates direct functionalization at the pyrrole ring.
2,4-Dichloropyrrolo[2,1-f][1,2,4]triazine serves as a versatile building block in medicinal chemistry, enabling efficient construction of nitrogen-rich heterocyclic scaffolds. The dichloro substituents facilitate direct nucleophilic substitution reactions under mild conditions, allowing rapid diversification at C2 and C4 positions. Its stability under standard reaction conditions and compatibility with common functional groups make it ideal for parallel synthesis campaigns targeting kinase inhibitors and other bioactive compounds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: