Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

B-Raf IN 11

  • CAS No. 918504-27-5

  • Cat. No. CS-M1934
  • Purity≥98%
  • MDL No.MFCD18207768

*For research and further manufacturing use only, not for direct human use.

B-Raf IN 11|CS-M1934

Structure of 918504-27-5

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 918504-27-5
  • Cat. No. CS-M1934
  • Purity ≥98%
  • MDL No. MFCD18207768
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₇H₁₄BrF₂N₃O₃S
  • Molecular Weight 458.28
  • Synonym(s) None
  • SMILES FC1=C(C(C2=CNC3=NC=C(Br)C=C32)=O)C(F)=C(NS(=O)(CCC)=O)C=C1

Description

B-Raf IN 11 is a potent, selective inhibitor of B-Raf kinase activity, designed for targeted disruption of the MAPK signaling pathway. This compound features a rigid heterocyclic core that enhances binding affinity and stability. It exhibits strong cellular potency against mutant B-Raf isoforms, enabling precise interrogation of oncogenic signaling in cancer models.

Application

B-Raf IN 11 serves as a well-characterized kinase inhibitor scaffold, enabling targeted disruption of B-Raf-mediated signaling pathways. Its structure facilitates selective interaction with the ATP-binding site of B-Raf, supporting utility in validating oncogenic RAS/RAF/MEK/ERK pathway activity. The compound exhibits bench-stable properties and compatibility with standard purification methods, making it suitable for use in cellular assays and mechanistic studies within medicinal chemistry workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   91.92
  • LogP   3.9863
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   6

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • B-Raf IN 11 sigmaB-Raf IN 11 manufacturerB-Raf IN 11 priceB-Raf IN 11 structureB-Raf IN 11 SDSbuy B-Raf IN 11B-Raf IN 11 supplierB-Raf IN 11 usesB-Raf IN 11 molecular weightprice of B-Raf IN 11B-Raf IN 11 chemical name formula of B-Raf IN 11
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label