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Structure of 918328-16-2
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This boronate-functionalized phenylmethanol integrates readily into Suzuki-Miyaura coupling reactions under standard conditions. The methylsulfonyl group enhances solubility and stability, while the tetramethylboronate moiety enables efficient cross-coupling with aryl halides. This bench-stable reagent streamlines access to complex biaryl architectures in medicinal chemistry and materials synthesis.
(2-(Methylsulfonyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanol serves as a versatile boronate building block for Suzuki-Miyaura coupling reactions. The pendant methanol group offers enhanced solubility and facilitates downstream functionalization, while the methylsulfonyl moiety provides strong electron-withdrawing character and metabolic stability. Bench-stable and compatible with a broad range of reaction conditions, it enables efficient construction of biaryl scaffolds in medicinal chemistry and materials synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H312-H332
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501
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Lot numbers can be found on the outside label of a product: