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CS-W001157 4
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2-Chloro-5,7-dimethylquinoline-3-carbonitrile

  • CAS No. 917747-10-5

  • Cat. No. CS-0321830
  • Molecule weight216.67
  • Purity95+%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-Chloro-5,7-dimethylquinoline-3-carbonitrile|CS-0321830

Structure of 917747-10-5

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General Information

  • CAS No. 917747-10-5
  • Cat. No. CS-0321830
  • Purity 95+%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₉ClN₂
  • Molecular Weight 216.67
  • Synonym(s) 2-Chloro-5,7-dimethyl-quinoline-3-carbonitrile
  • SMILES CC1=CC(=C2C=C(C#N)C(=NC2=C1)Cl)C

Synthesis

  • Route1
    • 2-Chloro-5,7-dimethylquinoline-3-carbaldehyde|CS-0280392
      482639-32-7
    • ~95%
    • 2-Chloro-5,7-dimethylquinoline-3-carbonitrile|CS-0321830
      917747-10-5

    References

    • THE REGENTS OF THE UNIVERSITY OF CALIFORNIA; VERKMAN, Alan S.; PHUAN, Puay-Wah; KURTH, Mark J.; KNAPP, John Patent: WO2012/166654 A1, 2012 ; Location in patent: Page/Page column 87 ; WO 2012/166654 A1
  • Route2
    • N-(3,5-Dimethylphenyl)acetamide|CS-0280842
      2050-45-5
    • ~%
    • 2-Chloro-5,7-dimethylquinoline-3-carbonitrile|CS-0321830
      917747-10-5

    References

    • Knapp, John M.; Wood, Alex B.; Phuan, Puay-Wah; Lodewyk, Michael W.; Tantillo, Dean J.; Verkman; Kurth, Mark J. Journal of Medicinal Chemistry, 2012 , vol. 55, # 3 p. 1242 - 1251
  • Route3
    • null|null
      108-69-0
    • ~%
    • 2-Chloro-5,7-dimethylquinoline-3-carbonitrile|CS-0321830
      917747-10-5

    References

    • Knapp, John M.; Wood, Alex B.; Phuan, Puay-Wah; Lodewyk, Michael W.; Tantillo, Dean J.; Verkman; Kurth, Mark J. Journal of Medicinal Chemistry, 2012 , vol. 55, # 3 p. 1242 - 1251

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301
Precautionary Statements : P264-P270-P330-P405-P501

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Computational Chemistry Data

  • TPSA   36.68
  • LogP   3.37672
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

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