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CS-W001157 4
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(R)-1-Methyl-4-(pyrrolidin-3-yl)piperazine trihydrochloride

  • CAS No. 917505-14-7

  • Cat. No. CS-0698176
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(R)-1-Methyl-4-(pyrrolidin-3-yl)piperazine trihydrochloride|CS-0698176

Structure of 917505-14-7

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General Information

  • CAS No. 917505-14-7
  • Cat. No. CS-0698176
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₂₂Cl₃N₃
  • Molecular Weight 278.65
  • Synonym(s) None
  • SMILES Cl.Cl.Cl.CN1CCN(CC1)[C@@H]1CCNC1

Description

(R)-1-Methyl-4-(pyrrolidin-3-yl)piperazine trihydrochloride is a chiral piperazine derivative featuring a tertiary amine center and a pyrrolidinyl substituent. This bench-stable, moisture-tolerant salt integrates readily into medicinal chemistry libraries, offering enhanced solubility and defined stereochemistry for targeted receptor engagement in CNS-directed drug discovery.

Application

(R)-1-Methyl-4-(pyrrolidin-3-yl)piperazine trihydrochloride serves as a versatile, bench-stable building block for medicinal chemistry campaigns. Its tertiary amine core enables straightforward salt formation and enhances solubility in aqueous media. The molecule functions effectively in coupling reactions and supports the construction of complex heterocyclic scaffolds common in CNS-targeted therapeutics. Functional group tolerance and ease of purification make it well-suited for high-throughput synthesis and process-scale applications.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   18.51
  • LogP   0.8611
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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