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CS-W001157 4
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1,1,1-Trifluoro-N-((trifluoromethyl)sulfonyl)methanesulfonamide, cesium salt

  • CAS No. 91742-16-4

  • Cat. No. CS-0499117
  • Purity≥98%
  • MDL No.MFCD29472520

*For research and further manufacturing use only, not for direct human use.

1,1,1-Trifluoro-N-((trifluoromethyl)sulfonyl)methanesulfonamide, cesium salt|CS-0499117

Structure of 91742-16-4

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General Information

  • CAS No. 91742-16-4
  • Cat. No. CS-0499117
  • Purity ≥98%
  • MDL No. MFCD29472520
  • Storage RT, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂HCsF₆NO₄S₂
  • Molecular Weight 414.06
  • Synonym(s) Cesium(I) Triflimide
  • SMILES O=S(NS(=O)(C(F)(F)F)=O)(C(F)(F)F)=O.[Cs]

Description

This trifluoromethylsulfonamide derivative features a cesium-stabilized anion with exceptional solubility in polar aprotic solvents, enabling efficient deprotonation in synthetic transformations. The fully fluorinated sulfonamide scaffold imparts high thermal and oxidative stability, while the cesium counterion enhances reactivity in nucleophilic substitution processes.

Application

1,1,1-Trifluoro-N-((trifluoromethyl)sulfonyl)methanesulfonamide, cesium salt serves as a stable, bench-ready trifluoromethylating agent with enhanced solubility in polar aprotic solvents. It enables efficient electrophilic trifluoromethylation of nucleophiles under mild conditions, offering high functional group tolerance and compatibility with complex molecular architectures. The cesium counterion facilitates smooth reaction kinetics and simplifies purification, making it a practical choice for synthetic workflows requiring selective C–CF₃ bond formation.

Safety Information

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GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group : Ⅱ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501

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Computational Chemistry Data

  • TPSA   80.31
  • LogP   -0.3733
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   2

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