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Structure of 917397-92-3
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1-(5-Bromopyridin-2-yl)-2,2,2-trifluoroethanol features a brominated pyridine moiety paired with a trifluoromethyl-bearing alcohol, enabling direct incorporation into cross-coupling and functionalization workflows. The electron-deficient pyridine ring enhances reactivity in palladium-catalyzed transformations, while the trifluoromethyl group imparts enhanced metabolic stability and lipophilicity. This compound serves as a valuable synthon for bioactive molecule synthesis.
1-(5-Bromopyridin-2-yl)-2,2,2-trifluoroethanol serves as a versatile building block for constructing brominated heterocyclic scaffolds in medicinal chemistry and materials science. The trifluoromethyl group enhances metabolic stability and lipophilicity, while the bromopyridine moiety enables subsequent cross-coupling reactions such as Suzuki-Miyaura and Stille coupling. Its bench-stable crystalline form facilitates handling and purification, making it ideal for scalable synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: