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CS-W001157 4
Total: USD 88.00

5,6-Dimethoxybenzo[b]thiophene

  • CAS No. 91715-47-8

  • Cat. No. CS-0044111
  • Purity≥98%
  • MDL No.MFCD00981875

*For research and further manufacturing use only, not for direct human use.

5,6-Dimethoxybenzo[b]thiophene|CS-0044111

Structure of 91715-47-8

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General Information

  • CAS No. 91715-47-8
  • Cat. No. CS-0044111
  • Purity ≥98%
  • MDL No. MFCD00981875
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₀O₂S
  • Molecular Weight 194.25
  • Synonym(s) Benzo[b]thiophene, 5,6-dimethoxy-
  • SMILES COC1=C(OC)C=C(C=CS2)C2=C1

Description

5,6-Dimethoxybenzo[b]thiophene features two methoxy groups flanking the benzo ring, enhancing electron density and solubility in organic media. This bench-stable heterocycle integrates readily into synthetic sequences requiring electron-rich aromatic scaffolds, particularly in pharmaceutical intermediates and materials chemistry applications.

Application

5,6-Dimethoxybenzo[b]thiophene serves as a versatile heterocyclic building block in medicinal chemistry and materials science. The dimethoxy substitution pattern enhances solubility and modulates electronic properties, while the benzo[b]thiophene core provides a rigid, planar scaffold suitable for cross-coupling reactions. Its bench-stable nature and compatibility with Pd-catalyzed transformations facilitate efficient synthesis of complex architectures.

Synthesis

  • Route1

    References

    • Bew; Clemo Journal of the Chemical Society, 1953 , p. 1314 Full Text Show Details Campaigne; Cline Journal of Organic Chemistry, 1956 , vol. 21, p. 32,35
  • Route2
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    • In-stock
      5,6-Dimethoxybenzo[b]thiophene|CS-0044111
      91715-47-8

    References

    • Campaigne; Cline Journal of Organic Chemistry, 1956 , vol. 21, p. 32,35
  • Route3
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      872284-72-5
    • ~%
    • In-stock
      5,6-Dimethoxybenzo[b]thiophene|CS-0044111
      91715-47-8

    References

    • Campaigne; Cline Journal of Organic Chemistry, 1956 , vol. 21, p. 32,35

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   18.46
  • LogP   2.9185
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   2

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