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Structure of 916889-45-7
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Ethyl 5-bromo-1,3,4-oxadiazole-2-carboxylate features a brominated oxadiazole core that enables direct functionalization in cross-coupling reactions. This bench-stable, moisture-tolerant reagent integrates readily into synthetic sequences requiring electrophilic halogen handles. The ester group enhances solubility in common organic solvents and supports downstream derivatization.
Ethyl 5-bromo-1,3,4-oxadiazole-2-carboxylate serves as a versatile building block in heterocyclic synthesis, enabling efficient access to functionalized oxadiazoles via palladium-catalyzed cross-coupling reactions. The bromo group facilitates C–C bond formation under standard Suzuki, Stille, or Negishi conditions, while the ester functionality supports further derivatization. Its bench-stable nature and compatibility with diverse functional groups make it well-suited for iterative synthetic strategies in medicinal chemistry and materials science.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: