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CS-W001157 4
Total: USD 88.00

4-(1-Methyl-1H-pyrazol-3-yl)aniline

  • CAS No. 916766-82-0

  • Cat. No. CS-0151173
  • Purity≥95%
  • MDL No.MFCD03407387

*For research and further manufacturing use only, not for direct human use.

4-(1-Methyl-1H-pyrazol-3-yl)aniline|CS-0151173

Structure of 916766-82-0

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General Information

  • CAS No. 916766-82-0
  • Cat. No. CS-0151173
  • Purity ≥95%
  • MDL No. MFCD03407387
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₁N₃
  • Molecular Weight 173.21
  • Synonym(s) 4-(1-methylpyrazol-3-yl)aniline
  • SMILES CN1C=CC(=N1)C2=CC=C(C=C2)N

Description

4-(1-Methyl-1H-pyrazol-3-yl)aniline features a pyrazole ring fused to an aniline scaffold, delivering enhanced electronic coupling and solubility. The methylated pyrazole moiety imparts steric stability and improved metabolic resistance, while the para-aniline group enables straightforward coupling reactions. This compound serves as a key intermediate in the synthesis of bioactive heterocycles and functional materials.

Application

4-(1-Methyl-1H-pyrazol-3-yl)aniline serves as a versatile building block in medicinal chemistry, enabling the construction of biologically relevant heterocyclic scaffolds. Its pyrazole ring exhibits robust bench stability and compatibility with standard coupling reactions, while the aniline functionality facilitates further derivatization via electrophilic substitution or amide formation. The molecule demonstrates excellent functional group tolerance and ease of purification, making it well-suited for high-throughput synthesis and process-scale applications.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   43.84
  • LogP   1.6693
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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