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Structure of 916304-19-3
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This trifluoromethyl-substituted pyridylmethanamine features a polar, electron-deficient pyridine ring paired with a primary amine handle, enabling straightforward functionalization. The para-trifluoromethyl group enhances metabolic stability and modulates electronic properties, making it valuable in medicinal chemistry and catalyst design.
(6-(Trifluoromethyl)pyridin-2-yl)methanamine serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through standard coupling and functionalization reactions. Its trifluoromethyl group enhances metabolic stability and modulates electronic properties, while the primary amine facilitates conjugation with carboxylic acids, aldehydes, and electrophiles. The compound exhibits good bench stability, ease of purification, and compatibility with common protecting group strategies, making it a reliable scaffold for API development and lead optimization.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 2735
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H315-H318-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501
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Lot numbers can be found on the outside label of a product: