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(S)-5-Bromo-2,3-dihydro-1H-inden-1-amine hydrochloride

  • CAS No. 916210-93-0

  • Cat. No. CS-0095533
  • Purity≥97%
  • MDL No.MFCD21603637

*For research and further manufacturing use only, not for direct human use.

(S)-5-Bromo-2,3-dihydro-1H-inden-1-amine hydrochloride|CS-0095533

Structure of 916210-93-0

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General Information

  • CAS No. 916210-93-0
  • Cat. No. CS-0095533
  • Purity ≥97%
  • MDL No. MFCD21603637
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₁BrClN
  • Molecular Weight 248.55
  • Synonym(s) None
  • SMILES N[C@H]1CCC2=C1C=CC(Br)=C2.[H]Cl

Description

(S)-5-Bromo-2,3-dihydro-1H-inden-1-amine hydrochloride is a chiral amine scaffold featuring a brominated indene core, offering high stereochemical integrity and stability under standard conditions. The hydrochloride salt enhances solubility and handling, enabling efficient integration into asymmetric synthesis workflows. This compound serves as a key intermediate in medicinal chemistry for constructing bioactive heterocycles.

Application

(S)-5-Bromo-2,3-dihydro-1H-inden-1-amine hydrochloride serves as a versatile chiral building block for the synthesis of indoline-based scaffolds. Its well-defined stereochemistry and bromo functionality enable efficient palladium-catalyzed cross-coupling reactions, facilitating access to biologically relevant heterocycles. The hydrochloride salt enhances bench stability and solubility in polar solvents, simplifying handling and purification in synthetic workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   26.02
  • LogP   2.8169
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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