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CS-W001157 4
Total: USD 88.00

(3-Chloro-5-cyanophenyl)boronic acid

  • CAS No. 915763-60-9

  • Cat. No. CS-W018738
  • Purity≥96%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(3-Chloro-5-cyanophenyl)boronic acid|CS-W018738

Structure of 915763-60-9

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General Information

  • CAS No. 915763-60-9
  • Cat. No. CS-W018738
  • Purity ≥96%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₅BClNO₂
  • Molecular Weight 181.38
  • Synonym(s) 3-Chloro-5-cyanophenylboronicacid
  • SMILES N#CC1=CC(Cl)=CC(B(O)O)=C1

Description

(3-Chloro-5-cyanophenyl)boronic acid features a boronate moiety appended to a heteroaromatic scaffold bearing chlorine and nitrile groups. This configuration enables direct incorporation into Suzuki-Miyaura coupling reactions under standard conditions, delivering functionalized biaryls with high efficiency. The electron-withdrawing cyano group enhances reactivity while maintaining bench-stable handling characteristics.

Application

(3-Chloro-5-cyanophenyl)boronic acid serves as a versatile building block in Suzuki-Miyaura coupling reactions, enabling efficient C–C bond formation under mild conditions. Its compatibility with diverse reaction partners, combined with bench-stable boronic acid functionality and orthogonal reactivity of the chloro and cyano groups, facilitates downstream functionalization in medicinal chemistry and materials synthesis.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   64.25
  • LogP   -0.10852
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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