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CS-W001157 4
Total: USD 88.00

1,2-Dideoxy-D-ribofuranose

  • CAS No. 91547-59-0

  • Cat. No. CS-0089202
  • Purity≥95%
  • MDL No.MFCD01630918

*For research and further manufacturing use only, not for direct human use.

1,2-Dideoxy-D-ribofuranose|CS-0089202

Structure of 91547-59-0

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General Information

  • CAS No. 91547-59-0
  • Cat. No. CS-0089202
  • Purity ≥95%
  • MDL No. MFCD01630918
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₀O₃
  • Molecular Weight 118.13
  • Synonym(s) None
  • SMILES OC[C@@H]1[C@@H](O)CCO1

Description

1,2-Dideoxy-D-ribofuranose is a key carbohydrate scaffold lacking hydroxyl groups at the 1 and 2 positions, conferring enhanced stability and reduced reactivity. This configuration enables selective functionalization at C3 and C4, facilitating use in glycosylation studies and nucleoside analog synthesis. The furanose ring maintains conformational rigidity under standard conditions, supporting precise stereochemical control in synthetic pathways.

Application

1,2-Dideoxy-D-ribofuranose serves as a key building block in carbohydrate chemistry, enabling the synthesis of nucleoside analogs and glycosylation intermediates. Its stable furanose ring and defined stereochemistry facilitate selective functionalization at C3 and C4 positions. The absence of hydroxyl groups at C1 and C2 enhances its stability under acidic conditions and simplifies purification, making it valuable for constructing complex oligosaccharides and evaluating glycosidase substrate specificity in medicinal and biochemical research.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   49.69
  • LogP   -0.8715
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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