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CS-W001157 4
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3,7-Dichloro-1-(2-propoxyethyl)pyrido[3,4-b]pyrazin-2(1H)-one

  • CAS No. 915307-81-2

  • Cat. No. CS-0545280
  • Molecule weight302.16
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

3,7-Dichloro-1-(2-propoxyethyl)pyrido[3,4-b]pyrazin-2(1H)-one|CS-0545280

Structure of 915307-81-2

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General Information

  • CAS No. 915307-81-2
  • Cat. No. CS-0545280
  • Purity ≥98%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₃Cl₂N₃O₂
  • Molecular Weight 302.16
  • Synonym(s) 3,7-Dichloro-1-(2-propoxyethyl)-1H,2H-pyrido-[3,4-b]pyrazin-2-one
  • SMILES CCCOCCN1C2=CC(=NC=C2N=C(C1=O)Cl)Cl

Synthesis

  • Route1
    • null|null
      5781-53-3
    • 6-Chloro-N4-(2-propoxyethyl)pyridine-3,4-diamine|CS-0562798
      915307-80-1
    • ~65%
    • 3,7-Dichloro-1-(2-propoxyethyl)pyrido[3,4-b]pyrazin-2(1H)-one|CS-0545280
      915307-81-2

    References

    • PHARMACIA and UPJOHN COMPANY LLC Patent: WO2006/126082 A2, 2006 ; Location in patent: Page/Page column 61 ;
  • Route2
    • null|null
      1186508-07-5
    • ~82%
    • 3,7-Dichloro-1-(2-propoxyethyl)pyrido[3,4-b]pyrazin-2(1H)-one|CS-0545280
      915307-81-2

    References

    • Hughes, Robert O.; Walker, John K.; Cubbage, Jerry W.; Fobian, Yvette M.; Rogier, D. Joseph; Heasley, Steve E.; Blevis-Bal, Rhadika M.; Benson, Alan G.; Owen, Dafydd R.; Jacobsen, E. Jon; Freskos, John N.; Molyneaux, John M.; Brown, David L.; Stallings, William C.; Acker, Brad A.; Maddux, Todd M.; Tollefson, Mike B.; Williams, Jennifer M.; Moon, Joseph B.; Mischke, Brent V.; Rumsey, Jeanne M.; Zheng, Yi; MacInnes, Alan; Bond, Brian R.; Yu, Ying Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 15 p. 4092 - 4096

Safety Information

Download SDS
GHS Pictogram : N/A
GHS No : N/A
Signal Word : N/A
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

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Computational Chemistry Data

  • TPSA   57.01
  • LogP   2.5249
  • H_Acceptors   5
  • H_Donors   0
  • Rotatable_Bonds   5

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