Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

4-Amino-2-fluoro-N-methylbenzamide

  • CAS No. 915087-25-1

  • Cat. No. CS-M1520
  • Purity≥98%
  • MDL No.MFCD09909322

*For research and further manufacturing use only, not for direct human use.

4-Amino-2-fluoro-N-methylbenzamide|CS-M1520

Structure of 915087-25-1

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 915087-25-1
  • Cat. No. CS-M1520
  • Purity ≥98%
  • MDL No. MFCD09909322
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₉FN₂O
  • Molecular Weight 168.17
  • Synonym(s) N-Methyl-4-amino-2-fluoro-benzamide
  • SMILES O=C(NC)C1=C(F)C=C(N)C=C1

Description

4-Amino-2-fluoro-N-methylbenzamide features a strategically positioned para-amino group and ortho-fluoro substituent on a benzamide scaffold, enabling selective coupling reactions in medicinal chemistry. The N-methyl substitution enhances metabolic stability while maintaining solubility under standard conditions. This compound serves as a key intermediate for bioactive molecule synthesis.

Application

4-Amino-2-fluoro-N-methylbenzamide serves as a versatile building block in medicinal chemistry, enabling direct incorporation of both amino and fluoro functionalities into target molecules. Its N-methyl amide group enhances metabolic stability and modulates lipophilicity, while the ortho-fluoro substituent facilitates directed ortho-metalation and influences electronic properties. The compound exhibits excellent bench stability and is compatible with standard coupling reactions, simplifying access to complex heterocyclic scaffolds and API intermediates.

Synthesis

  • Route1
    • null|null
      956104-46-4
    • ~99%
    • In-stock
      4-Amino-2-fluoro-N-methylbenzamide|CS-M1520
      915087-25-1

    References

    • SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH Patent: WO2008/119015 A2, 2008 ; Location in patent: Page/Page column 52-53 ;
  • Route2

    References

    • TONG, Youzhi Patent: WO2011/29392 A1, 2011 ; Location in patent: Page/Page column 62-63 ; WO 2011/029392 A1
  • Route3

    References

    • TONG, Youzhi Patent: WO2011/29392 A1, 2011 ; WO 2011/029392 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   55.12
  • LogP   0.7675
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 4-Amino-2-fluoro-N-methylbenzamide sigma4-Amino-2-fluoro-N-methylbenzamide manufacturer4-Amino-2-fluoro-N-methylbenzamide price4-Amino-2-fluoro-N-methylbenzamide structure4-Amino-2-fluoro-N-methylbenzamide SDSbuy 4-Amino-2-fluoro-N-methylbenzamide4-Amino-2-fluoro-N-methylbenzamide supplier4-Amino-2-fluoro-N-methylbenzamide uses4-Amino-2-fluoro-N-methylbenzamide molecular weightprice of 4-Amino-2-fluoro-N-methylbenzamide4-Amino-2-fluoro-N-methylbenzamide chemical name formula of 4-Amino-2-fluoro-N-methylbenzamide
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label