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CS-W001157 4
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2-(4-((3-Amino-6-bromoquinolin-4-yl)amino)phenyl)-2-methylpropanenitrile

  • CAS No. 915019-52-2

  • Cat. No. CS-B0356
  • Molecule weight381.27
  • Purity≥97%
  • MDL No.MFCD12408068

*For research and further manufacturing use only, not for direct human use.

2-(4-((3-Amino-6-bromoquinolin-4-yl)amino)phenyl)-2-methylpropanenitrile|CS-B0356

Structure of 915019-52-2

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General Information

  • CAS No. 915019-52-2
  • Cat. No. CS-B0356
  • Purity ≥97%
  • MDL No. MFCD12408068
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₉H₁₇BrN₄
  • Molecular Weight 381.27
  • Synonym(s) 2-(4-((3-Amino-6-bromoquinolin-4-yl)amino)-phenyl)-2-methylpropanenitrile
  • SMILES N#CC(C)(C)C(C=C1)=CC=C1NC2=C(N)C=NC3=CC=C(Br)C=C23

Synthesis

  • Route1
    • 2-(4-((6-Bromo-3-nitroquinolin-4-yl)amino)phenyl)-2-methylpropanenitrile|CS-B0355
      915019-51-1
    • ~86%
    • 2-(4-((3-Amino-6-bromoquinolin-4-yl)amino)phenyl)-2-methylpropanenitrile|CS-B0356
      915019-52-2

    References

    • INTELLIKINE, LLC; REN, Pingda; LIU, Yi; LI, Liansheng; CHAN, Katrina; WILSON, Troy, Edward; CAMPBELL, Simon, Fraser Patent: WO2012/116237 A2, 2012 ; Location in patent: Page/Page column 119 ; WO 2012/116237 A2
  • Route2

    References

    • PIRAMAL LIFE SCIENCES LIMITED; KUMAR, Sanjay; VISHWAKARMA, Ram; MUNDADA, Ramswaroop; DEORE, Vijaykumar; KUMAR, Pramod; SHARMA, Somesh Patent: WO2011/1212 A1, 2011 ; WO 2011/001212 A1
  • Route3

    References

    • PIRAMAL LIFE SCIENCES LIMITED; KUMAR, Sanjay; VISHWAKARMA, Ram; MUNDADA, Ramswaroop; DEORE, Vijaykumar; KUMAR, Pramod; SHARMA, Somesh Patent: WO2011/1212 A1, 2011 ; WO 2011/001212 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

Quality Control

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Computational Chemistry Data

  • TPSA   74.73
  • LogP   5.12428
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   3

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