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CS-W001157 4
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6-Morpholin-4-ylpyridazine-3-carboxylic acid

  • CAS No. 914637-36-8

  • Cat. No. CS-0070395
  • Purity≥97%
  • MDL No.MFCD08235211

*For research and further manufacturing use only, not for direct human use.

6-Morpholin-4-ylpyridazine-3-carboxylic acid|CS-0070395

Structure of 914637-36-8

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General Information

  • CAS No. 914637-36-8
  • Cat. No. CS-0070395
  • Purity ≥97%
  • MDL No. MFCD08235211
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₁N₃O₃
  • Molecular Weight 209.20
  • Synonym(s) 6-Morpholinopyridazine-3-carboxylic acid
  • SMILES O=C(O)C(C=C1)=NN=C1N2CCOCC2

Description

6-Morpholin-4-ylpyridazine-3-carboxylic acid features a pyridazine core functionalized with a morpholine ring and a carboxylic acid group, enabling strong hydrogen bonding and enhanced solubility. This scaffold integrates readily into bioactive molecules, offering favorable pharmacokinetic properties through improved polarity and metabolic stability.

Application

6-Morpholin-4-ylpyridazine-3-carboxylic acid serves as a versatile building block for medicinal chemistry, enabling the construction of bioactive heterocycles through standard coupling and cyclization protocols. Its carboxylic acid functionality facilitates amide bond formation and salt crystallization, while the morpholinyl and pyridazinyl moieties offer favorable solubility and metabolic stability. The compound exhibits bench-stable handling and compatibility with diverse reaction conditions, making it well-suited for lead optimization and API scaffold development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H312-H332
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501

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Computational Chemistry Data

  • TPSA   75.55
  • LogP   0.0114
  • H_Acceptors   5
  • H_Donors   1
  • Rotatable_Bonds   2

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