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Structure of 914452-70-3
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2-Iodo-5-methylpyrazine is a bench-stable, moisture-tolerant heterocyclic iodide featuring a methyl group at the 5-position and an iodine atom at the 2-position. This configuration enables direct coupling in cross-coupling reactions, facilitating efficient access to functionalized pyrazine scaffolds. The electron-deficient core supports palladium-catalyzed transformations with high regioselectivity.
2-Iodo-5-methylpyrazine serves as a versatile building block in heterocyclic synthesis, enabling palladium-catalyzed cross-coupling reactions with broad functional group tolerance. Its iodine moiety facilitates efficient C–C and C–heteroatom bond formation, while the methyl group enhances solubility and stability. This compound functions reliably in standard coupling protocols, offering predictable reactivity for constructing complex pyrazine-based scaffolds in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: