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CS-W001157 4
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Methyl 2-iodonicotinate

  • CAS No. 913836-18-7

  • Cat. No. CS-0313103
  • Purity≥97%
  • MDL No.MFCD08689498

*For research and further manufacturing use only, not for direct human use.

Methyl 2-iodonicotinate|CS-0313103

Structure of 913836-18-7

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General Information

  • CAS No. 913836-18-7
  • Cat. No. CS-0313103
  • Purity ≥97%
  • MDL No. MFCD08689498
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₆INO₂
  • Molecular Weight 263.03
  • Synonym(s) METHYL 2-IODO-3-PYRIDINECARBOXYLATE
  • SMILES COC(=O)C1=C(I)N=CC=C1

Description

Methyl 2-iodonicotinate is a bench-stable, moisture-tolerant iodinated pyridine derivative featuring a strategically positioned ester group. This compound integrates readily into cross-coupling workflows, serving as a direct precursor for C–C bond formation at the pyridine 2-position. The iodine moiety enables efficient palladium-catalyzed transformations under standard conditions.

Application

Methyl 2-iodonicotinate serves as a versatile building block in synthetic organic chemistry, enabling palladium-catalyzed cross-coupling reactions due to its stable iodide functionality. Its pyridine core provides orthogonal reactivity for late-stage functionalization, while the ester group offers compatibility with standard reduction and derivatization protocols. Bench-stable and readily purified by flash chromatography, it facilitates efficient access to substituted nicotinates and heterocyclic scaffolds relevant to medicinal chemistry and agrochemical development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

Quality Control

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Computational Chemistry Data

  • TPSA   39.19
  • LogP   1.4728
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   1

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