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CS-W001157 4
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6-Chloropyridine-2-sulfonyl chloride

  • CAS No. 913287-21-5

  • Cat. No. CS-0156793
  • Purity≥97%
  • MDL No.MFCD11846921

*For research and further manufacturing use only, not for direct human use.

6-Chloropyridine-2-sulfonyl chloride|CS-0156793

Structure of 913287-21-5

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General Information

  • CAS No. 913287-21-5
  • Cat. No. CS-0156793
  • Purity ≥97%
  • MDL No. MFCD11846921
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₃Cl₂NO₂S
  • Molecular Weight 212.05
  • Synonym(s) 6-CHLORO-PYRIDINE-2-SULFONYL CHLORIDE
  • SMILES C1=CC(=NC(=C1)S(=O)(=O)Cl)Cl

Description

6-Chloropyridine-2-sulfonyl chloride features a reactive sulfonyl chloride group flanked by a chlorine-substituted pyridine ring, enabling direct incorporation into heterocyclic scaffolds. This bench-stable electrophile facilitates efficient derivatization in synthetic and medicinal chemistry workflows.

Application

6-Chloropyridine-2-sulfonyl chloride serves as a versatile acylating agent for the installation of sulfonamide functionalities in medicinal chemistry and agrochemical synthesis. Its reactivity enables efficient formation of sulfonamide derivatives under mild conditions, with the chloropyridine scaffold offering enhanced stability and compatibility with diverse functional groups. The compound facilitates straightforward purification and is well-suited for scale-up in process-oriented applications.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS06
Signal Word : Danger
UN#: 3261
Class : 8
Packing Group : Ⅲ
Hazard Statements : H301-H311-H314-H331
Precautionary Statements : P260-P264-P270-P271-P280-P301+P330+P331-P302+P352-P304+P340-P405-P501

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Computational Chemistry Data

  • TPSA   47.03
  • LogP   1.6625
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   1

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