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Structure of 913287-14-6
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Ethyl 4-fluoro-7-nitro-1H-indole-2-carboxylate features a fluorinated indole core with electron-withdrawing nitro and ester functionalities, enabling direct incorporation into complex heterocyclic architectures. This bench-stable reagent streamlines access to bioactive indole derivatives in medicinal chemistry workflows.
Ethyl 4-fluoro-7-nitro-1H-indole-2-carboxylate serves as a versatile building block for the synthesis of substituted indole scaffolds, enabling late-stage functionalization via palladium-catalyzed cross-coupling. The electron-deficient indole core facilitates nucleophilic substitution at C4, while the nitro group supports sequential transformations in medicinal chemistry campaigns. Bench-stable and amenable to purification by flash chromatography, it functions effectively in standard synthetic workflows requiring orthogonality between nitro, fluoro, and ester functionalities.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: