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CS-W001157 4
Total: USD 88.00

2,7-Diazaspiro[4.4]nonane-1,3,8-trione, 2-methyl-

  • CAS No. 91189-24-1

  • Cat. No. CS-0000846
  • Molecule weight182.18
  • Purity95+%
  • MDL No.MFCD01305634

*For research and further manufacturing use only, not for direct human use.

2,7-Diazaspiro[4.4]nonane-1,3,8-trione, 2-methyl-|CS-0000846

Structure of 91189-24-1

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General Information

  • CAS No. 91189-24-1
  • Cat. No. CS-0000846
  • Purity 95+%
  • MDL No. MFCD01305634
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₀N₂O₃
  • Molecular Weight 182.18
  • Synonym(s) 2-Methyl-2,7-diazaspiro[4.4]nonane-1,3,8-trione
  • SMILES O=C(C1(CC(NC1)=O)CC2=O)N2C

Synthesis

  • Route1
    • Ethyl 3-(2-ethoxy-2-oxoethyl)-5-oxopyrrolidine-3-carboxylate|CS-0974122
      91189-23-0
    • ~%
    • 2,7-Diazaspiro[4.4]nonane-1,3,8-trione, 2-methyl-|CS-0000846
      91189-24-1

    References

    • Warner-Lambert Company Patent: US4604401 A1, 1986 ;
  • Route2
    • Ethyl 3-(2-ethoxy-2-oxoethyl)-5-oxopyrrolidine-3-carboxylate|CS-0974122
      91189-23-0
    • null|null
      74-89-5
    • ~74%
    • 2,7-Diazaspiro[4.4]nonane-1,3,8-trione, 2-methyl-|CS-0000846
      91189-24-1

    References

    • Culbertson, Townley P.; Sanchez, Joseph P.; Gambino, Laura; Sesnie, Josephine A. Journal of Medicinal Chemistry, 1990 , vol. 33, # 8 p. 2270 - 2275
  • Route3
    • Triethyl 2-cyanopropane-1,2,3-tricarboxylate|CS-0571785
      20822-61-1
    • ~%
    • 2,7-Diazaspiro[4.4]nonane-1,3,8-trione, 2-methyl-|CS-0000846
      91189-24-1

    References

    • Culbertson, Townley P.; Sanchez, Joseph P.; Gambino, Laura; Sesnie, Josephine A. Journal of Medicinal Chemistry, 1990 , vol. 33, # 8 p. 2270 - 2275

Safety Information

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GHS Pictogram : N/A
GHS No : N/A
Signal Word : N/A
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

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Computational Chemistry Data

  • TPSA   66.48
  • LogP   -1.1186
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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