Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

5-Iodo-3-(trifluoromethyl)pyridin-2-amine

  • CAS No. 911112-05-5

  • Cat. No. CS-0103372
  • Purity≥98%
  • MDL No.MFCD16250855

*For research and further manufacturing use only, not for direct human use.

5-Iodo-3-(trifluoromethyl)pyridin-2-amine|CS-0103372

Structure of 911112-05-5

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 911112-05-5
  • Cat. No. CS-0103372
  • Purity ≥98%
  • MDL No. MFCD16250855
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₄F₃IN₂
  • Molecular Weight 288.01
  • Synonym(s) 5-Iodo-3-(trifluoromethyl)-2-pyridinamine
  • SMILES NC1=NC=C(C=C1C(F)(F)F)I

Description

5-Iodo-3-(trifluoromethyl)pyridin-2-amine features a reactive iodine handle at the 5-position paired with an electron-deficient trifluoromethyl group, enabling efficient cross-coupling transformations. The pyridin-2-amine scaffold provides a rigid, polar platform for modular assembly in medicinal chemistry and materials science applications.

Application

5-Iodo-3-(trifluoromethyl)pyridin-2-amine serves as a versatile building block in medicinal chemistry and cross-coupling methodologies. The iodide moiety enables reliable Suzuki, Stille, and Buchwald-Hartwig coupling reactions, while the trifluoromethyl group enhances metabolic stability and lipophilicity. The pyridine nitrogen provides coordination capability and improves solubility. This compound exhibits excellent bench stability and is readily purified by flash chromatography, facilitating integration into multi-step synthetic sequences for targeted heterocyclic scaffolds.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   38.91
  • LogP   2.2872
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 911112-05-5 sigma911112-05-5 manufacturer911112-05-5 price911112-05-5 structure911112-05-5 SDSbuy 911112-05-5911112-05-5 supplier911112-05-5 uses911112-05-5 molecular weightprice of 911112-05-5911112-05-5 chemical name formula of 911112-05-5
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label