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Structure of 908600-70-4
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5-Fluoro-1H-indole-4-carboxylic acid features a fluorinated indole core with a carboxylic acid group at the 4-position, offering enhanced electron-withdrawing character and improved metabolic stability. This scaffold integrates readily into bioactive molecules for medicinal chemistry campaigns targeting CNS agents and kinase inhibitors.
5-Fluoro-1H-indole-4-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of indole-based scaffolds with enhanced metabolic stability. Its carboxylic acid functionality facilitates direct amidation, esterification, and coupling reactions, while the fluorinated position offers favorable electronic effects for target engagement. The compound exhibits good bench stability and is compatible with standard peptide coupling protocols, making it suitable for high-throughput library generation and API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: