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CS-W001157 4
Total: USD 88.00

(3-(Hydroxymethyl)-4-methoxyphenyl)boronic acid

  • CAS No. 908142-03-0

  • Cat. No. CS-0042817
  • Purity≥98%
  • MDL No.MFCD14155851

*For research and further manufacturing use only, not for direct human use.

(3-(Hydroxymethyl)-4-methoxyphenyl)boronic acid|CS-0042817

Structure of 908142-03-0

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General Information

  • CAS No. 908142-03-0
  • Cat. No. CS-0042817
  • Purity ≥98%
  • MDL No. MFCD14155851
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₁BO₄
  • Molecular Weight 181.98
  • Synonym(s) 3-Hydroxymethyl-4-methoxyphenylboronic acid
  • SMILES COC1=CC=C(B(O)O)C=C1CO

Description

This boronic acid features a hydroxymethyl group ortho to the boronate, enhancing solubility and stability. The para-methoxy substituent imparts electron-donating character, improving coupling efficiency in Suzuki-Miyaura reactions. Bench-stable and moisture-tolerant, it integrates seamlessly into complex molecule synthesis workflows.

Application

(3-(Hydroxymethyl)-4-methoxyphenyl)boronic acid serves as a versatile building block for Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl and heteroaryl scaffolds. Its boronic acid functionality exhibits good bench stability and compatibility with diverse functional groups, facilitating straightforward purification and integration into complex molecular architectures.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   69.92
  • LogP   -1.1327
  • H_Acceptors   4
  • H_Donors   3
  • Rotatable_Bonds   3

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