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CS-W001157 4
Total: USD 88.00

2,3-Dichloro-4-fluorobenzonitrile

  • CAS No. 908123-82-0

  • Cat. No. CS-0197493
  • Molecule weight190.00
  • Purity≥96%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2,3-Dichloro-4-fluorobenzonitrile|CS-0197493

Structure of 908123-82-0

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General Information

  • CAS No. 908123-82-0
  • Cat. No. CS-0197493
  • Purity ≥96%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₂Cl₂FN
  • Molecular Weight 190.00
  • Synonym(s) None
  • SMILES N#CC1=CC=C(F)C(Cl)=C1Cl

Description

2,3-Dichloro-4-fluorobenzonitrile features a trifunctional aromatic core with chlorine, fluorine, and nitrile groups positioned for orthogonal reactivity. This electron-deficient scaffold enables selective coupling in cross-coupling reactions and serves as a key building block in pharmaceutical and agrochemical synthesis.

Application

2,3-Dichloro-4-fluorobenzonitrile serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling direct introduction of fluorine and chlorine substituents in electron-deficient aromatic systems. Its nitrile group facilitates nucleophilic addition and subsequent transformations, while the ortho-dichloro substitution pattern supports palladium-catalyzed cross-coupling reactions. The compound exhibits good bench stability and is compatible with standard purification protocols, making it suitable for multi-step syntheses requiring functional group tolerance and predictable reactivity.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

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Computational Chemistry Data

  • TPSA   23.79
  • LogP   3.00418
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   0

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