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Structure of 90357-51-0
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N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-methyloxirane-2-carboxamide features a trifluoromethyl-substituted aryl group paired with a strained oxirane ring bearing a carboxamide functionality. This configuration enables direct incorporation into bioactive scaffolds, where the electrophilic epoxide facilitates covalent targeting, and the nitrile and trifluoromethyl groups enhance metabolic stability and lipophilicity.
N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-methyloxirane-2-carboxamide serves as a versatile building block for the synthesis of functionalized heterocycles and bioactive scaffolds. The oxirane moiety enables regioselective ring opening under mild conditions, while the nitrile and trifluoromethyl groups provide enhanced metabolic stability and lipophilic character. This compound exhibits bench stability and facilitates efficient derivatization in medicinal chemistry campaigns, particularly in the development of kinase inhibitors and CNS-targeted molecules.
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GHS Pictogram :
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GHS No : GHS07,GHS08
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302+H312+H332-H315-H319-H341
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: