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CS-W001157 4
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5-Methoxybenzo[d]thiazole-2-carboxylic acid

  • CAS No. 90322-41-1

  • Cat. No. CS-0197487
  • Molecule weight209.22
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

5-Methoxybenzo[d]thiazole-2-carboxylic acid|CS-0197487

Structure of 90322-41-1

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General Information

  • CAS No. 90322-41-1
  • Cat. No. CS-0197487
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₇NO₃S
  • Molecular Weight 209.22
  • Synonym(s) 5-Methoxybenzothiazole-2-carboxylic acid
  • SMILES COC1=CC2=C(C=C1)SC(=N2)C(=O)O

Description

5-Methoxybenzo[d]thiazole-2-carboxylic acid features a fused benzothiazole core with a methoxy group at the 5-position and a carboxylic acid at the 2-position. This combination imparts enhanced solubility and electronic modulation, enabling direct incorporation into bioactive scaffolds. The molecule exhibits bench-stable handling characteristics and serves as a key building block for pharmaceutical intermediates and functional materials.

Application

5-Methoxybenzo[d]thiazole-2-carboxylic acid serves as a versatile heterocyclic building block in medicinal chemistry, enabling the synthesis of bioactive scaffolds via standard coupling reactions. Its carboxylic acid functionality facilitates amide bond formation, while the methoxy group provides moderate electron donation and enhances solubility. The benzo[d]thiazole core offers structural rigidity and metabolic stability, making it suitable for parallel library synthesis and drug discovery campaigns requiring robust, bench-stable intermediates.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   59.42
  • LogP   2.0031
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   2

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