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Structure of 903129-71-5
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tert-Butyl 2,4-dichloro-5H-pyrrolo[3,4-d]pyrimidine-6(7H)-carboxylate is a bench-stable, moisture-tolerant heterocyclic building block featuring two chlorine substituents at electron-deficient positions. This derivative enables direct incorporation into purine-based scaffolds via palladium-catalyzed cross-coupling, streamlining access to functionalized pyrrolopyrimidines for medicinal chemistry applications.
tert-Butyl 2,4-dichloro-5H-pyrrolo[3,4-d]pyrimidine-6(7H)-carboxylate serves as a versatile building block for purine-derived heterocycles, enabling efficient functionalization at the C2 and C4 positions. Its dichloro substitution pattern facilitates palladium-catalyzed cross-coupling reactions, while the tert-butyl ester group offers stability and ease of removal under mild acidic conditions. The scaffold exhibits excellent functional group tolerance and is well-suited for iterative synthesis of kinase inhibitor candidates and nucleoside analogs in medicinal chemistry workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: